Alpha GPC Capsules

Alpha-GPC capsules offer an excellent source of choline.✝

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Bottle of 120 caps x 400mg



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What is Alpha GPC?

Alpha-GPC (α-glycerophosphocholine, aka choline alphoscerate) is a good acetylcholine precursor.1 Glycerophosphocholine is widespread in our metabolism and forms membrane phospholipids.

Alpha-GPC is best known for its effects on cognitive functions, such as attention, mental focus and recall, but some recent evidence suggests that alpha-GPC supplementation may also lead to physiological and physical improvements. For example, acute supplementation of alpha-GPC has been shown to increase growth hormone response to resistance exercise in young men.2

Another study supported these results by demonstrating that a single 1000 mg dose of alpha-GPC increases growth hormone secretion and hepatic fat oxidation in young adults.4 These findings have important practical implications for all fitness enthusiasts you are looking to increase growth hormone levels and fat oxidation. The effects of six days supplementation with alpha-GPC have also been tested on isometric strength in young males.3 They found that alpha-GPC significantly improved lower body force production compared to placebo.3

Key benefits:

  • Memory formation & development
  • Improved focus & attention
  • Higher concentration
  • Enhanced learning
  • Better mood

Mechanisms of action:

After oral administration, Alpha GPC is converted to phosphorylcholine, which is a metabolically active form of choline and then transported to cholinergic nerve terminals where it increases the levels of acetylcholine by stimulating its synthesis and release.

Recommended dosage:

The recommended dosage of alpha-GPC is 400 mg per day. Alpha-GPC is a water-soluble form of choline and appears to be effective over the course of 24 hours, however a peak concentration in plasma free choline is normally observed 1-2 hours post administration.4

Side effects:

Alpha GPC is regarded as safe if taken at the recommended dosage. However, cognitive stimulation is sometimes reported as a side effect. Typical side effects from overdosing include headaches and restlessness. You can prevent these side effects by lowering the daily dosage.

Bioavailability of Alpha GPC:

Following oral ingestion Alpha GPC increases plasma choline levels. Choline is then used by the brain tissue. For example, after taking 1000 mg of oral Alpha GPC there was an increase of serum choline concentrations from 8.1 mmol/L to 12.1 mmol/L in young healthy male subjects. The neural and blood concentrations are very similar, which makes Alpha GPC a highly effective nootropic.  

Supplement facts:

Serving size: 1 capsule

Servings per bottle: 120

Amount per serving: Alpha GPC 400 mg

Other ingredients: Magnesium Stearate; Silicon Dioxide

This product is free from: Artificial flavours, colours & preservatives, Lactose, Yeast & Gluten

Suitable for: Vegetarians and Vegans


  • Dietary supplements should not be used as a substitute for a well-balanced and healthy diet.
  • Store in a cool dry place, out of reach of children.
  • Do not use if you are pregnant or breastfeeding.


  1. Alpha-GPC
  1. Ziegenfuss, T. et al. (2008). Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. J Int Soc Sports Nutr, 5 (suppl 1), p15.
  1. Bellar, D. et al. (2015). The effect of 6 days of alpha-glycerylphosphorylcholine on isometric strength. J Int Soc Sports Nutr, 12, 42.
  1. Kawamura, T. et al. (2012). Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults. Nutrition, 28, 1122-6.


✝ These statements have not been evaluated by the Food and Drug Administration (FDA) The above products are not intended to diagnose, treat, cure or prevent any disease. You should consult a physician before taking a new product or a supplement. This product should not be taken by pregnant or nursing mothers, people suffering from cardiovascular disease or those under 18 years of age.

Any studies cited here are not conclusive and are limited to their closed environment nature; they might not determine ones experience with a supplement, due to a large number of unaccounted variables falling outside the scope of such studies.

The reviews available here are the opinions of contributors who may or may have not used these products, and do not necessarily represent the views of Orbivit. These reviews represent one’s opinion and should not be taken as fact or recommendation. Orbivit makes no warranty to the accuracy of information provided by these reviews. Read legal disclaimer

Alpha GPC Capsules Reviews

OrbiVit Alpha GPC Capsules

(based on 1 reviews)

By Tom C. on25 July 2017
Best source of choline
Alpha GPC from Orbivit is definitely the best source of choline I’ve ever bought and I have tried many online retailers! Continue producing excellent quality supplements!
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